Hypertrophic osteoarthropathy

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Hypertrophic osteoarthropathy
X-ray of a patient with hypertrophic osteoarthropathy
Synonyms Hypertrophic pulmonary osteoarthropathy, Bamberger-Marie syndrome
Pronounce N/A
Specialty Rheumatology, Pulmonology
Symptoms Clubbing of the fingers and toes, arthralgia, periostitis
Complications Joint effusion, pain, swelling
Onset Variable, often associated with underlying conditions
Duration Chronic
Types N/A
Causes Lung cancer, chronic lung infections, congenital heart disease
Risks Smoking, chronic respiratory disease
Diagnosis Clinical examination, X-ray, bone scan
Differential diagnosis Rheumatoid arthritis, osteoarthritis, thyroid acropachy
Prevention N/A
Treatment Treat underlying cause, NSAIDs, analgesics
Medication N/A
Prognosis Depends on underlying condition
Frequency Rare
Deaths N/A


Hypertrophic osteoarthropathy (HOA) is a medical condition characterized by abnormal proliferation of skin and bone tissue. The symptoms often include clubbing of the fingers and toes, increased sweating, and pain in the joints or bones.

Causes[edit]

The exact cause of hypertrophic osteoarthropathy is unknown. However, it is often associated with cancer, especially lung cancer. Other conditions that may cause HOA include lung disease, heart disease, and certain gastrointestinal disorders.

Symptoms[edit]

The most common symptoms of hypertrophic osteoarthropathy include:

  • Clubbing of the fingers and toes
  • Increased sweating
  • Pain in the joints or bones
  • Swelling of the legs or ankles
  • Thickening of the skin

Diagnosis[edit]

Diagnosis of hypertrophic osteoarthropathy is usually based on the patient's symptoms and a physical examination. Additional tests may be needed to confirm the diagnosis and rule out other conditions. These tests may include:

Treatment[edit]

Treatment for hypertrophic osteoarthropathy focuses on managing the symptoms and treating the underlying condition. This may include:

See also[edit]

References[edit]

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