Heterophyes heterophyes

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Heterophyes heterophyes

Life cycle of Heterophyes heterophyes

Heterophyes heterophyes is a species of trematode (fluke) that is a parasite of humans and other fish-eating mammals. It is a member of the family Heterophyidae. This small intestinal fluke is found in various parts of the world, particularly in regions where raw or undercooked fish is consumed.

Morphology

Heterophyes heterophyes is a small fluke, measuring about 1 to 1.7 mm in length and 0.3 to 0.4 mm in width. The body is covered with a tegument and has a characteristic pyriform shape. The oral sucker is located at the anterior end, and a ventral sucker is present slightly posterior to the oral sucker. The fluke has a simple digestive system with a pharynx, esophagus, and two intestinal ceca.

Life Cycle

The life cycle of Heterophyes heterophyes involves three hosts: a snail as the first intermediate host, a fish as the second intermediate host, and a mammal as the definitive host.

  1. Eggs: The life cycle begins when eggs are passed in the feces of the definitive host. These eggs are ingested by a suitable snail.
  2. Miracidia: Inside the snail, the eggs hatch into miracidia, which penetrate the snail's tissues.
  3. Sporocysts and Rediae: The miracidia develop into sporocysts, which then produce rediae.
  4. Cercariae: The rediae give rise to cercariae, which leave the snail and swim in the water.
  5. Metacercariae: The cercariae penetrate the skin or scales of a fish and encyst as metacercariae in the fish's tissues.
  6. Infection of Definitive Host: Humans or other mammals become infected by consuming raw or undercooked fish containing metacercariae. Once ingested, the metacercariae excyst in the small intestine, where they mature into adult flukes.

Pathogenesis and Clinical Features

Infection with Heterophyes heterophyes can lead to heterophyiasis, which is often asymptomatic but can cause gastrointestinal symptoms such as abdominal pain and diarrhea. In heavy infections, the flukes can invade the intestinal wall and cause inflammation. Rarely, they may migrate to other organs, leading to more severe complications.

Diagnosis

Diagnosis of Heterophyes heterophyes infection is typically made by identifying eggs in the stool of the infected individual. The eggs are small, ovoid, and have a characteristic operculum.

Treatment

The treatment of choice for Heterophyes heterophyes infection is praziquantel, an anthelmintic medication that is effective against a wide range of trematodes.

Related Pages

Template:Trematodes



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Contributors: Prab R. Tumpati, MD