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Hematological disorders are a broad range of conditions that affect the blood and its components. These disorders can be either benign (non-cancerous) or malignant (cancerous) and can affect the red blood cells, white blood cells, platelets, blood vessels, bone marrow, lymph nodes, spleen, and the proteins involved in bleeding and clotting.
Types of Hematological Disorders
There are several types of hematological disorders, including:
- Anemia: A condition characterized by a lack of healthy red blood cells or hemoglobin, the part of red blood cells that carries oxygen.
- Leukemia: A type of cancer that affects the bone marrow and blood.
- Lymphoma: A type of cancer that begins in the lymphatic system.
- Myeloma: A type of cancer that begins in the plasma cells in the bone marrow.
- Hemophilia: A rare disorder in which the blood doesn't clot normally because it lacks sufficient blood-clotting proteins.
- Thrombocytopenia: A condition in which you have a low blood platelet count.
- Polycythemia vera: A slow-growing blood cancer in which your bone marrow makes too many red blood cells.
Symptoms
The symptoms of hematological disorders can vary greatly depending on the specific disorder. However, common symptoms can include fatigue, weakness, shortness of breath, easy bruising or bleeding, frequent infections, and unexplained weight loss.
Diagnosis
Diagnosis of hematological disorders often involves blood tests, bone marrow tests, and sometimes genetic testing. The specific tests used will depend on the suspected disorder.
Treatment
Treatment for hematological disorders depends on the type and severity of the disorder, the person's age, and their overall health. Treatment options can include medication, blood transfusions, procedures to remove or replace diseased bone marrow, chemotherapy, radiation therapy, or targeted therapy.
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Contributors: Prab R. Tumpati, MD