Friability

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Friability

Friability (pronounced: /fraɪəˈbɪlɪti/) is a term used in pharmacology and material science to describe the physical property of a solid substance to be easily crumbled or pulverized.

Etymology

The term "friability" is derived from the Latin word "friabilis", which means "easily crumbled".

Definition

In pharmacology, friability is a test used to determine the physical strength of a tablet. The test is carried out by tumbling the tablets and then determining the percentage of weight loss. The United States Pharmacopeia (USP) states that tablets should not lose more than 1% of their weight in this test.

In material science, friability refers to the tendency of a material to break, crumble, or degrade under pressure or impact. This property is often used to assess the durability of materials, such as concrete or ceramics.

Related Terms

  • Abrasion: The process of scraping or wearing away, often discussed in relation to friability.
  • Compressibility: The property of being able to compact a substance, often inversely related to friability.
  • Hardness: A measure of resistance to deformation, often inversely related to friability.
  • Pharmaceutical formulation: The process in which different chemical substances are combined to produce a final medicinal product, often considering the friability of the product.

See Also

External links

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