Indium (111In) biciromab

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Indium (111In) biciromab



Trade names FibriScint






Pregnancy category N/A





Legal status Withdrawn
Identifiers
CAS Number 138783-13-8



ChemSpider none


KEGG D03111









Indium (111In) biciromab (INN, trade name FibriScint, developed by Centocor) was a drug targeting fibrin, a protein involved in the clotting of blood.[1] It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism,[2] but was withdrawn during clinical trials.[3]

References[edit]

  1. King, David J.."Recombinant antibodies for the diagnosis and therapy of human disease".Current Opinion in Drug Discovery & Development.1999;2(2)
    112.
  2. Answers.com: Centocor Ortho Biotech Products, L.P.
  3. DiagnosticImaging.com: Centocor withdraws imaging agent applications