Fenthion

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Fenthion Structural Formulae .V.1

Fenthion is an organophosphate insecticide and acaricide used to control a wide range of pests, including mosquitoes, flies, and other insects. It is known for its effectiveness in agricultural and public health applications.

Chemical Properties

Fenthion is a phosphorothioate ester, which means it contains a phosphorus atom bonded to a sulfur atom. Its chemical formula is C10H15O3PS2. It is a colorless to yellow-brown liquid with a faint odor.

Mode of Action

Fenthion works by inhibiting the enzyme acetylcholinesterase, which is essential for the proper functioning of the nervous system in insects. This inhibition leads to an accumulation of acetylcholine at nerve synapses, causing continuous nerve impulse transmission, paralysis, and eventually death of the insect.

Uses

Fenthion is used in various settings, including:

Environmental Impact

Fenthion is highly toxic to non-target organisms, including birds, fish, and bees. Its use is regulated in many countries to minimize environmental contamination and protect wildlife.

Safety and Regulation

Due to its toxicity, the use of fenthion is subject to strict regulations. Personal protective equipment (PPE) is recommended for individuals handling the chemical. In some regions, its use has been restricted or banned due to environmental and health concerns.

Related Compounds

Fenthion is part of a broader class of organophosphate insecticides, which includes other compounds such as malathion, parathion, and diazinon.

See Also

References



External Links


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Contributors: Prab R. Tumpati, MD