FCER1

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FCER1

FCER1 (pronounced as F-C-E-R-One), also known as High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha, is a protein that in humans is encoded by the FCER1A gene.

Etymology

The term FCER1 is an abbreviation for Fc Epsilon Receptor 1. The Fc part of the name refers to the Fragment crystallizable region of an antibody, epsilon (ε) refers to the type of antibody (IgE), and receptor indicates that it binds to a specific substance.

Function

FCER1 is a receptor that binds to the Fc region of immunoglobulin E (IgE), a type of antibody. This binding is a crucial part of the immune response, particularly in allergic reactions. The FCER1 receptor is found on the surface of certain immune cells, including mast cells and basophils.

Related Terms

  • Immunoglobulin E (IgE): A type of antibody that is primarily associated with allergic reactions. It binds to allergens and triggers an immune response.
  • Mast Cells: A type of white blood cell that plays a key role in the immune system, particularly in the response to allergens.
  • Basophils: A type of white blood cell that, like mast cells, is involved in the immune response to allergens.
  • Allergen: A substance that triggers an allergic reaction.

See Also

  • Allergy: A hypersensitivity disorder of the immune system.
  • Antibody: A protein produced by the body's immune system when it detects harmful substances.
  • Immune System: The body's defense against infectious organisms and other invaders.

External links

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