Extramedullary hematopoiesis
Extramedullary Hematopoiesis
Extramedullary hematopoiesis (pronounced: ex-tra-me-du-lar-ry he-ma-to-po-ie-sis) is a medical term that refers to the production of blood cells outside the bone marrow. This process is typically a compensatory response to insufficient production of blood cells within the bone marrow.
Etymology
The term "extramedullary hematopoiesis" is derived from the Latin words "extra" meaning outside, "medulla" meaning marrow, and "hematopoiesis" meaning the formation of blood or blood cells.
Related Terms
- Hematopoiesis: The process of forming blood cells, which normally occurs in the bone marrow.
- Medulla: The innermost part of something, in this case, the bone marrow.
- Erythropoiesis: The process of producing red blood cells.
- Myelopoiesis: The formation of bone marrow or of cells that form marrow.
- Leukopoiesis: The formation of white blood cells.
- Thrombopoiesis: The formation of platelets.
Clinical Significance
Extramedullary hematopoiesis is often seen in conditions where the bone marrow's capacity to produce blood cells is compromised, such as in myelofibrosis or thalassemia. It can also occur in response to severe anemia or hypoxia. The most common sites for extramedullary hematopoiesis are the liver and spleen, but it can also occur in other tissues such as the lymph nodes, thymus, and heart.
See Also
External links
- Medical encyclopedia article on Extramedullary hematopoiesis
- Wikipedia's article - Extramedullary hematopoiesis
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