Emetine
Emetine
Emetine (pronounced: /ˈɛmɪtiːn/) is a highly potent and toxic alkaloid derived from the root of the Ipecacuanha plant. It is primarily used as an anti-protozoal agent in the treatment of amoebiasis.
Etymology
The term 'Emetine' is derived from the Greek word 'emetos', meaning 'vomiting'. This is due to the drug's emetic properties, which can induce vomiting.
Usage
Emetine is used in the treatment of amoebiasis, a parasitic infection caused by the protozoan Entamoeba histolytica. It is also used as an emetic, a substance that induces vomiting, in cases of poisoning or drug overdose.
Pharmacology
Emetine works by inhibiting protein synthesis in the protozoan, leading to its death. It also stimulates the vomiting center in the brain, causing emesis.
Side Effects
Common side effects of emetine include nausea, vomiting, and abdominal pain. In rare cases, it can cause serious heart problems, including cardiomyopathy and heart failure.
Related Terms
- Ipecacuanha: The plant from which emetine is derived.
- Amoebiasis: A parasitic infection treated with emetine.
- Anti-protozoal: A class of drugs that includes emetine.
- Emetic: A substance that induces vomiting, like emetine.
- Cardiomyopathy: A potential side effect of emetine use.
External links
- Medical encyclopedia article on Emetine
- Wikipedia's article - Emetine
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