ERV-Fc
ERV-Fc is a protein that in humans is encoded by the ERV-Fc gene. ERV-Fc is a member of the endogenous retrovirus (ERV) family of genes. ERVs are remnants of ancient viral infections, and they comprise a significant portion of the human genome. ERV-Fc is one of the few ERVs that is still capable of producing a functional protein.
Function
The ERV-Fc protein is thought to play a role in the immune system. It is expressed in several types of immune cells, including T cells and B cells. The exact function of the ERV-Fc protein is not yet fully understood, but it is believed to be involved in the regulation of immune responses.
Clinical significance
Alterations in the ERV-Fc gene have been associated with several diseases. For example, overexpression of ERV-Fc has been observed in patients with autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus. In addition, mutations in the ERV-Fc gene have been linked to an increased risk of developing cancer.
Research
Research on ERV-Fc is ongoing, with scientists seeking to better understand the role of this gene in health and disease. This research could potentially lead to the development of new treatments for diseases associated with alterations in the ERV-Fc gene.
See also
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Contributors: Prab R. Tumpati, MD
