Domiphen bromide

From WikiMD's medical encyclopedia


Overview

Chemical structure of Domiphen Bromide

Domiphen Bromide is a quaternary ammonium compound that is widely used as an antiseptic and disinfectant. It is known for its effectiveness in killing bacteria and other microorganisms, making it a common ingredient in various antiseptic and disinfectant products.

Chemical Properties

Domiphen Bromide is a quaternary ammonium compound, which means it contains a positively charged nitrogen atom that is bonded to four organic groups. This structure is responsible for its ability to disrupt microbial cell membranes, leading to cell death.

Uses

Domiphen Bromide is used in a variety of applications, including:

  • Oral Care Products: It is often found in mouthwashes and toothpastes due to its ability to reduce oral bacteria and prevent gingivitis.
  • Skin Antiseptics: It is used in antiseptic creams and solutions for cleaning wounds and preventing infection.
  • Surface Disinfectants: Domiphen Bromide is used in cleaning products for disinfecting surfaces in hospitals and other healthcare settings.

Mechanism of Action

The antimicrobial activity of Domiphen Bromide is primarily due to its ability to disrupt the cell membranes of bacteria. The positively charged nitrogen atom interacts with the negatively charged components of the microbial cell membrane, leading to increased permeability and eventual cell lysis.

Safety and Precautions

While Domiphen Bromide is effective as an antiseptic, it should be used with caution. Prolonged exposure or high concentrations can cause irritation to the skin and mucous membranes. It is important to follow the recommended usage guidelines to avoid adverse effects.

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Contributors: Prab R. Tumpati, MD