Dinitrophenyl
Dinitrophenyl
Dinitrophenyl (pronunciation: di-ni-tro-phen-yl) is a chemical compound that is often used in scientific research, particularly in the field of immunology.
Etymology
The term "Dinitrophenyl" is derived from the Greek words "di" meaning two, "nitro" meaning nitrogen, and "phenyl" meaning aromatic hydrocarbon.
Description
Dinitrophenyl is a compound that consists of a phenyl group attached to two nitro groups. It is often used as a hapten in the production of antibodies. When attached to a protein, the dinitrophenyl group can stimulate an immune response, leading to the production of antibodies that specifically recognize and bind to dinitrophenyl. This property makes it useful in various immunological techniques, such as immunohistochemistry and ELISA.
Related Terms
- Hapten: A small molecule that can elicit an immune response only when attached to a large carrier such as a protein.
- Antibody: A protein produced by the body's immune system when it detects harmful substances, called antigens.
- Phenyl group: A functional group characterized by a phenyl ring, which is a ring of 6 carbon atoms to which hydrogen atoms are attached.
- Nitro group: A functional group consisting of one nitrogen atom connected by single bonds to two oxygen atoms.
- Immunohistochemistry: A method for detecting antigens or haptens in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues.
- ELISA: A plate-based assay technique designed for detecting and quantifying substances such as peptides, proteins, antibodies, and hormones.
External links
- Medical encyclopedia article on Dinitrophenyl
- Wikipedia's article - Dinitrophenyl
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