Dimetacrine

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Dimetacrine

Dimetacrine (pronounced dih-meh-tuh-kreen), also known as Istonil, Istonyl, Linostil, and Miroistonil, is a type of tricyclic antidepressant (TCA) that was formerly used in the treatment of depression but is now largely obsolete due to the development of newer and safer drugs.

Etymology

The term "Dimetacrine" is derived from the chemical structure of the drug, which contains two (di-) methyl (-met-) groups and an acridine (-acrine) group.

Pharmacology

Dimetacrine acts by inhibiting the reuptake of certain neurotransmitters in the brain, specifically norepinephrine and serotonin, thereby increasing their levels in the brain and leading to an improvement in mood. It also has anticholinergic properties, which can lead to side effects such as dry mouth, constipation, and blurred vision.

Related Terms

  • Tricyclic antidepressant: A class of drugs that includes Dimetacrine and is used to treat depression.
  • Norepinephrine: A neurotransmitter that is increased in the brain by Dimetacrine.
  • Serotonin: Another neurotransmitter that is increased in the brain by Dimetacrine.
  • Anticholinergic: A term describing the side effects of Dimetacrine, which are caused by its action on the cholinergic system.

See Also

External links

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