Diffuse axonal injury
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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| Diffuse axonal injury | |
|---|---|
| Synonyms | DAI |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Loss of consciousness, coma, vegetative state, cognitive impairment |
| Complications | Chronic traumatic encephalopathy, post-traumatic stress disorder |
| Onset | Traumatic brain injury |
| Duration | Variable |
| Types | Mild, moderate, severe |
| Causes | Acceleration-deceleration injury, rotational forces |
| Risks | Motor vehicle accidents, falls, sports injuries, assaults |
| Diagnosis | MRI, CT scan |
| Differential diagnosis | Concussion, contusion, intracerebral hemorrhage |
| Prevention | Seat belts, helmets, fall prevention |
| Treatment | Supportive care, rehabilitation, physical therapy, occupational therapy |
| Medication | N/A |
| Prognosis | Variable, depends on severity |
| Frequency | Common in severe traumatic brain injury |
| Deaths | N/A |
Diffuse axonal injury
Diffuse Axonal Injury (DAI) is a type of traumatic brain injury that is caused by the shearing forces that occur when the head is rapidly accelerated or decelerated, as in car accidents or falls. It is one of the most common and devastating types of traumatic brain injury, and it can result in significant impairment or death.
Causes
Diffuse axonal injury is caused by the shearing forces that occur when the head is rapidly accelerated or dececelerated. This can occur in a variety of situations, such as car accidents, falls, or violent assaults. The rapid movement of the head causes the brain to move within the skull, which can lead to damage to the brain's axons.
Symptoms
The symptoms of diffuse axonal injury can vary widely, depending on the severity of the injury. They can include loss of consciousness, confusion, dizziness, headache, nausea, vomiting, and other symptoms of a concussion. In more severe cases, symptoms can include coma, seizures, and other serious neurological problems.
Diagnosis
Diagnosis of diffuse axonal injury is typically made based on the patient's symptoms and the circumstances of the injury. Imaging tests, such as a CT scan or MRI, can also be used to confirm the diagnosis and assess the severity of the injury.
Treatment
Treatment for diffuse axonal injury is primarily supportive, as there is currently no cure for the condition. This can include measures to control symptoms, prevent complications, and support the patient's recovery. In some cases, surgery may be needed to relieve pressure on the brain.
Prognosis
The prognosis for patients with diffuse axonal injury can vary widely, depending on the severity of the injury. Some patients may recover with minimal long-term effects, while others may have significant neurological impairment or may not survive the injury.
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Contributors: Kondreddy Naveen, Prab R. Tumpati, MD