De Simone Formulation
De Simone Formulation is a specific blend of live probiotic strains with a high concentration of Lactobacillus and Bifidobacteria. It was developed by Professor Claudio De Simone, an Italian scientist, and is used in several probiotic products worldwide.
History
The De Simone Formulation was first developed in the 1990s by Professor Claudio De Simone. He aimed to create a probiotic blend that could help maintain a healthy gut microbiota and support the immune system. The formulation has been used in over 60 clinical studies and is recognized for its safety and efficacy.
Composition
The De Simone Formulation consists of a blend of eight different strains of bacteria: four strains of Lactobacilli (L. acidophilus, L. plantarum, L. paracasei, and L. delbrueckii subsp. bulgaricus), three strains of Bifidobacteria (B. longum, B. breve, and B. infantis), and one strain of Streptococcus thermophilus.
Clinical Studies
Numerous clinical studies have been conducted on the De Simone Formulation, demonstrating its potential benefits in various health conditions. These include Irritable Bowel Syndrome (IBS), Ulcerative Colitis, Pouchitis, and HIV-related gut disorders.
Use in Probiotic Products
The De Simone Formulation is used in several probiotic products worldwide, including Visbiome and Vivomixx. These products are used to help maintain a healthy gut microbiota and support the immune system.
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Contributors: Prab R. Tumpati, MD