Cryopyrin-associated periodic syndromes

Cryopyrin-associated periodic syndromes (CAPS) are a group of rare, hereditary autoinflammatory diseases characterized by episodes of inflammation and fever. The term "cryopyrin" comes from the Greek words "kryos" (cold) and "pyrin" (fire), reflecting the symptoms of cold-induced fever and inflammation.

Pronunciation

Cryopyrin-associated periodic syndromes is pronounced as kryo-pyrin-associated periodic syndromes.

Etymology

The term "Cryopyrin" is derived from the Greek words "kryos" meaning cold and "pyrin" meaning fire. This is in reference to the symptoms of cold-induced fever and inflammation that are characteristic of these syndromes.

Related Terms

• Autoinflammatory diseases
• Fever
• Inflammation
• Hereditary diseases

Symptoms

The symptoms of CAPS can vary greatly, but they often include:

• Fever
• Skin rash
• Joint pain
• Eye inflammation
• Fatigue

Diagnosis

Diagnosis of CAPS is typically based on the presence of characteristic symptoms and confirmed by genetic testing for mutations in the NLRP3 gene.

Treatment

Treatment for CAPS typically involves medications to reduce inflammation and control symptoms. These may include:

• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Corticosteroids
• Biologic agents

Prognosis

The prognosis for individuals with CAPS can vary depending on the specific syndrome and the severity of symptoms. However, with appropriate treatment, most individuals with CAPS can lead normal lives.

See Also

• Autoinflammatory diseases
• Hereditary diseases
• Inflammation
• Fever

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