Coriobacteriaceae

From WikiMD's medical encyclopedia

Family of bacteria



Overview

The Coriobacteriaceae are a family of Gram-positive bacteria within the phylum Actinomycetota. This family is part of the class Coriobacteriia and the order Coriobacteriales. Members of this family are known for their role in the human microbiome, particularly in the gastrointestinal tract.

Characteristics

Coriobacteriaceae are typically non-motile and non-spore-forming. They are anaerobic or microaerophilic, meaning they thrive in environments with little to no oxygen. These bacteria are known for their ability to metabolize complex carbohydrates and contribute to the fermentation processes in the gut.

Genera

The family Coriobacteriaceae includes several genera, such as:

Each genus has unique characteristics and plays specific roles in the microbiome. For example, Coriobacterium glomerans is known for its presence in the gut and its potential impact on host metabolism.

Role in the Human Microbiome

Coriobacteriaceae are significant members of the gut microbiota. They are involved in the breakdown of dietary fibers and the production of short-chain fatty acids, which are important for colon health and metabolic regulation. These bacteria also interact with the host's immune system, influencing immune response and inflammation.

Clinical Significance

Alterations in the abundance of Coriobacteriaceae have been associated with various health conditions, including obesity, inflammatory bowel disease, and cardiovascular disease. Understanding the role of these bacteria in health and disease is an active area of research.

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Contributors: Prab R. Tumpati, MD