Combination
Combination (kɒmbɪˈneɪʃən)
The term "Combination" (from the Latin combinare, meaning "to join two or more things together") is a fundamental concept in various fields of study, including medicine. In a medical context, combination often refers to the use of two or more drugs or treatments together to achieve a greater effect or to combat multiple symptoms or conditions simultaneously.
Medical Usage
In medicine, a combination therapy is the use of more than one medication or treatment modality to treat a single disease. This approach is often used in the management of complex diseases such as cancer, HIV/AIDS, and tuberculosis. The rationale behind combination therapy is to increase the efficacy of treatment, reduce the risk of drug resistance, and decrease side effects.
A combination drug is a fixed-dose combination (FDC) of two or more active pharmaceutical ingredients (APIs) in a single dosage form. This is commonly used in the treatment of a wide range of conditions, including hypertension, diabetes, and asthma.
Related Terms
- Synergism: The interaction of two or more agents or forces so that their combined effect is greater than the sum of their individual effects. In medicine, this often refers to the enhanced effect of multiple drugs used together.
- Polypharmacy: The concurrent use of multiple medications by a patient, often for multiple conditions. This is common in elderly patients and those with chronic illnesses.
- Drug interaction: A situation in which a substance affects the activity of a drug when both are administered together. This can enhance or decrease the effectiveness of the drugs, or cause adverse effects.
External links
- Medical encyclopedia article on Combination
- Wikipedia's article - Combination
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