Collier's sign
Collier's Sign
Collier's Sign (pronunciation: /ˈkɒliəz saɪn/), also known as Posterior Fossa Syndrome, is a medical term named after the British neurologist, James Collier (1870–1935).
Etymology
The term "Collier's Sign" is derived from the name of its discoverer, James Collier. He first described this clinical sign in 1927.
Definition
Collier's Sign is a clinical sign characterized by bilateral, symmetrical, upward gaze palsy. This is due to the involvement of the rostral midbrain and is often associated with hydrocephalus, brainstem tumors, and cerebellar hemorrhage.
Symptoms
The primary symptom of Collier's Sign is an inability to move the eyes upward. This is often accompanied by retraction nystagmus, a condition where the eyes make repetitive, uncontrolled movements. Other symptoms may include headache, nausea, and vomiting.
Diagnosis
Diagnosis of Collier's Sign is primarily based on clinical examination. The patient's inability to move their eyes upward, despite normal downward gaze, is a key indicator. Further diagnostic tests may include MRI or CT scan to identify any underlying conditions causing the sign.
Treatment
Treatment for Collier's Sign focuses on addressing the underlying cause. This may involve surgery to remove a tumor or to relieve hydrocephalus. Medications may also be used to manage symptoms.
Related Terms
- Rostral midbrain
- Hydrocephalus
- Brainstem tumors
- Cerebellar hemorrhage
- Retraction nystagmus
- MRI
- CT scan
External links
- Medical encyclopedia article on Collier's sign
- Wikipedia's article - Collier's sign
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