Collectin
Collectin
Collectin (pronounced kuh-lek-tin) is a type of protein that plays a crucial role in the immune system. It is part of the C-type lectin family, which is known for its ability to bind to carbohydrates in a calcium-dependent manner.
Etymology
The term "collectin" is derived from the words "collagen" and "lectin", indicating its structural and functional characteristics. The term was first used in the late 20th century.
Function
Collectins are involved in the innate immune response, which is the body's first line of defense against pathogens. They recognize and bind to foreign substances, such as bacteria and viruses, and facilitate their removal from the body. Collectins include proteins such as Mannose-binding lectin (MBL), Surfactant proteins A and D (SP-A and SP-D), and others.
Related Terms
- C-type lectin: A type of protein that can bind to carbohydrates. Collectins are a subtype of C-type lectins.
- Mannose-binding lectin (MBL): A type of collectin that plays a key role in the immune response to infection.
- Surfactant proteins A and D (SP-A and SP-D): Types of collectins found in the lungs that help protect against respiratory infections.
See Also
External links
- Medical encyclopedia article on Collectin
- Wikipedia's article - Collectin
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