Colesevelam hydrochloride

Colesevelam Hydrochloride

Colesevelam hydrochloride (pronunciation: koh-les-EV-a-lam hy-dro-KLOR-ide) is a type of medication used primarily to treat hypercholesterolemia (high cholesterol) and type 2 diabetes.

Etymology

The name "Colesevelam" is derived from the components of the drug itself. "Cole" refers to the bile acid sequestrant class of drugs, "sevel" is a unique identifier, and "am" signifies the presence of an amine group in the chemical structure. The term "hydrochloride" refers to the hydrochloride salt form of the drug, which enhances its solubility.

Pharmacology

Colesevelam hydrochloride belongs to the class of medications known as bile acid sequestrants. These drugs work by binding to bile acids in the intestine, preventing their reabsorption. This results in a decrease in the level of cholesterol in the blood. In addition, colesevelam hydrochloride has been shown to improve glycemic control in patients with type 2 diabetes.

Related Terms

• Bile acid sequestrants
• Hypercholesterolemia
• Type 2 diabetes
• Medication
• Cholesterol
• Glycemic control

See Also

• List of medications for hypercholesterolemia
• List of medications for type 2 diabetes

References

• DrugBank. (n.d.). Colesevelam. Retrieved from https://www.drugbank.ca/drugs/DB00930
• MedlinePlus. (n.d.). Colesevelam. Retrieved from https://medlineplus.gov/druginfo/meds/a699047.html

External links

• Medical encyclopedia article on Colesevelam hydrochloride
• Wikipedia's article - Colesevelam hydrochloride

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