Cobb syndrome

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Cobb Syndrome

Cobb Syndrome (pronounced: /kɒb/), also known as Cutaneomeningospinal Angiomatosis, is a rare medical condition first described by Bertram Cobb in 1915. The syndrome is characterized by the presence of spinal arteriovenous malformations (AVMs) and cutaneous hemangiomas in the same dermatome.

Etymology

The syndrome is named after the American neurologist, Bertram Cobb, who first described the condition. The term "syndrome" is derived from the Greek word "σύνδρομον" (syndromon), meaning "concurrence of symptoms" or "running together".

Symptoms

Cobb Syndrome typically presents with cutaneous hemangiomas, which are benign tumors of the blood vessels that appear on the skin. These are often accompanied by spinal arteriovenous malformations (AVMs), which are abnormal connections between the arteries and veins in the spinal cord. Other symptoms may include back pain, muscle weakness, and neurological deficits.

Diagnosis

Diagnosis of Cobb Syndrome is typically made through a combination of clinical examination, magnetic resonance imaging (MRI), and angiography. The presence of cutaneous hemangiomas and spinal AVMs in the same dermatome is a key diagnostic feature.

Treatment

Treatment for Cobb Syndrome is primarily focused on managing the symptoms and preventing complications. This may involve surgery to remove the AVMs, radiation therapy, or endovascular embolization.

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