Cloprostenol
Cloprostenol (pronounced klo-pros-ten-ol) is a synthetic prostaglandin analogue that is primarily used in veterinary medicine. It is a potent luteolytic agent, used to manipulate the estrous cycle of livestock by inducing luteolysis, the regression of the corpus luteum.
Etymology
The term "Cloprostenol" is derived from the chemical structure of the compound. The prefix "Clo-" refers to chlorine, a component of the compound, while "prostenol" is a common suffix for prostaglandin analogues.
Pharmacology
Cloprostenol functions by binding to prostaglandin F2alpha (PGF2α) receptors, which are found in high concentrations in the corpus luteum. This binding triggers a cascade of events that ultimately leads to luteolysis. The regression of the corpus luteum results in a rapid drop in progesterone levels, which can trigger estrus and/or parturition in livestock.
Usage
In veterinary medicine, cloprostenol is used to control the timing of estrus and parturition in livestock, particularly in swine and cattle. It is also used to treat certain reproductive disorders, such as pyometra and chronic endometritis.
Related Terms
See Also
External links
- Medical encyclopedia article on Cloprostenol
- Wikipedia's article - Cloprostenol
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