Clone (B-cell)

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Clone (B-cell)

Clone (B-cell) (pronunciation: /kləʊn/ (B-sel)) is a term used in Immunology to refer to a population of identical B cells, all derived from a single parent cell.

Etymology

The term 'clone' is derived from the Ancient Greek word 'klōn', meaning 'twig'. In the context of B-cells, it refers to the process of clonal expansion, where a single B-cell multiplies to form a group of cells with identical antibody receptors.

Definition

A Clone (B-cell) is a group of B-cells that are genetically identical and are all descendants of a single parent B-cell. This clonal population is produced in response to an antigen stimulus, with each B-cell clone producing a unique antibody that specifically recognizes the stimulating antigen.

Related Terms

  • Clonal Selection: The theory that the immune system responds to antigens by selecting and expanding the clones of B-cells that can recognize and bind to the antigen.
  • Clonal Expansion: The process by which a B-cell clone proliferates in response to antigen stimulation.
  • Antibody: A protein produced by B-cells that recognizes and binds to specific antigens.
  • Antigen: A substance that stimulates the immune system to produce antibodies.

See Also

External links

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