Memory B cell
Memory B cell
Memory B cells are a type of B cell that are formed following primary infection. They are a part of the adaptive immune system and play a crucial role in the immune response to subsequent infections.
Pronunciation
Memory B cell: /ˈmɛməri biː sɛl/
Etymology
The term "Memory B cell" is derived from the English words "memory" and "B cell". "Memory" refers to the ability of these cells to remember antigens they have previously encountered, while "B cell" is short for "Bursa-equivalent cell", referring to their development in the bursa of Fabricius in birds, or bone marrow in mammals.
Function
Memory B cells are responsible for the secondary immune response. Upon re-exposure to the same antigen, these cells can rapidly differentiate into plasma cells and produce antibodies specific to the antigen, providing a quicker and more effective immune response.
Development
Memory B cells develop from activated B cells that have undergone somatic hypermutation and class switch recombination during a primary immune response. They persist in the body for a long time, providing long-term immunity.
Related Terms
- Antigen
- B cell
- Plasma cell
- Antibody
- Somatic hypermutation
- Class switch recombination
- Primary immune response
- Secondary immune response
External links
- Medical encyclopedia article on Memory B cell
- Wikipedia's article - Memory B cell
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