Chordin
Chordin is a protein that in humans is encoded by the CHRD gene. Chordin plays a crucial role in embryonic development by regulating the BMP signaling pathway. It is involved in the organization of the body plan and the development of organs and tissues.
Function[edit]
Chordin is a glycoprotein that inhibits the BMP signaling pathway. It binds to BMPs, preventing them from interacting with their receptors. This inhibition is relieved by the action of the Tolloid family of metalloproteases, which cleave Chordin to release BMPs.
Clinical significance[edit]
Mutations in the CHRD gene have been associated with a variety of congenital disorders, including scoliosis, craniosynostosis, and heart defects.
See also[edit]
References[edit]
<references />
External links[edit]
 | This medical article is a stub. You can help WikiMD by expanding the page. |
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
