Carnoy's solution
Carnoy's Solution
Carnoy's solution (pronunciation: /kɑːˈnɔɪz səˈluːʃən/) is a fixative used in Histology and Pathology. It is named after the Belgian biologist Leo Carnoy, who first formulated it.
Etymology
The term "Carnoy's solution" is derived from the name of its inventor, Leo Carnoy, a Belgian biologist who was a prominent figure in the field of cellular biology during the late 19th and early 20th centuries.
Composition
Carnoy's solution is a mixture of Acetic acid, Chloroform, and Ethanol. The typical formulation is 6 parts of ethanol, 3 parts of chloroform, and 1 part of acetic acid.
Usage
In histology and pathology, Carnoy's solution is used as a fixative to preserve tissues for microscopic examination. It is particularly useful for preserving the fine details of cell nuclei and mitotic spindles.
Related Terms
- Fixative: A substance used to preserve biological tissues.
- Histology: The study of the microscopic structure of tissues.
- Pathology: The study of disease, its causes, processes, development, and consequences.
- Cell Nucleus: The central part of a cell that contains most of its genetic material.
- Mitotic Spindle: The structure that separates the chromosomes during cell division.
See Also
External links
- Medical encyclopedia article on Carnoy's solution
- Wikipedia's article - Carnoy's solution
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