Capsazepine
Capsazepine (pronounced cap-sa-ze-peen) is a synthetic compound that is commonly used in scientific research. It is known for its ability to act as a selective antagonist for the Transient Receptor Potential Vanilloid 1 (TRPV1), a protein that plays a crucial role in the human body's detection and regulation of body temperature, as well as in the inflammatory response to injury.
Etymology
The term "Capsazepine" is derived from "capsaicin," the active component of chili peppers that produces a burning sensation, and "azepine," a seven-membered heterocyclic chemical compound. The "capsa" part of the name refers to the genus Capsicum to which chili peppers belong.
Usage
Capsazepine is primarily used in scientific research to study the role and function of TRPV1. It is often used in experiments involving pain perception, inflammation, and body temperature regulation. It has also been used in studies investigating the potential therapeutic uses of TRPV1 antagonists in conditions such as obesity, asthma, and neuropathic pain.
Related Terms
- Transient Receptor Potential Vanilloid 1 (TRPV1)
- Capsaicin
- Antagonist
- Inflammation
- Neuropathic Pain
- Asthma
- Obesity
See Also
External links
- Medical encyclopedia article on Capsazepine
- Wikipedia's article - Capsazepine
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