CURB-65

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CURB-65

CURB-65 (pronounced "kerb-sixty-five") is a clinical prediction rule that has been validated for predicting mortality in community-acquired pneumonia and infection of any site. The name is an acronym for each of the risk factors measured. Each risk factor scores one point, for a maximum score of 5:

  • Confusion of new onset (defined as an AMTS of 8 or less)
  • Urea greater than 7 mmol/l (19 mg/dL)
  • Respiratory rate of 30 breaths per minute or greater
  • Blood pressure less than 90 systolic or diastolic blood pressure 60 or less
  • Age 65 or older

Etymology

The term CURB-65 is derived from the initial letters of the five risk factors. It was first proposed in a 2003 study by Lim et al. in the journal Thorax.

Related Terms

  • Pneumonia - An inflammatory condition of the lung primarily affecting the small air sacs known as alveoli.
  • Clinical prediction rule - A type of clinical decision support system that provides a statistical method for quantifying the individual contributions that various components of the history, physical examination, and basic laboratory results make toward the diagnosis, prognosis, or likely response to treatment in a patient.
  • Blood urea nitrogen - A medical test that measures the amount of urea nitrogen found in blood.
  • Blood pressure - The pressure of circulating blood on the walls of blood vessels.
  • Respiratory rate - The number of breaths a person takes per minute.

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