CUMYL-4CN-BINACA
CUMYL-4CN-BINACA
CUMYL-4CN-BINACA is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the cannabinoid receptors, which are part of the endocannabinoid system in the human body. This compound is part of a class of synthetic cannabinoids that are often found in products marketed as "legal highs" or "herbal incense."
Chemical Structure and Properties
CUMYL-4CN-BINACA is chemically classified as an indazole-based synthetic cannabinoid. Its structure includes a cyano group attached to the phenyl ring, which is believed to contribute to its high potency. The compound is designed to mimic the effects of tetrahydrocannabinol (THC), the primary psychoactive component of cannabis.
Pharmacology
As a synthetic cannabinoid, CUMYL-4CN-BINACA acts on the CB1 receptor and CB2 receptor, which are G protein-coupled receptors in the central nervous system and peripheral nervous system. The activation of these receptors by CUMYL-4CN-BINACA can lead to a range of effects, including altered perception, mood changes, and impaired motor function.
Legal Status
Due to its potential for abuse and lack of medical use, CUMYL-4CN-BINACA is classified as a controlled substance in many countries. The legal status of synthetic cannabinoids can vary widely, with some jurisdictions implementing specific bans on these compounds.
Health Effects and Risks
The use of CUMYL-4CN-BINACA has been associated with adverse health effects, including tachycardia, hypertension, nausea, and vomiting. In severe cases, it can lead to psychosis, seizures, and even death. The variability in potency and the presence of unknown adulterants in products containing synthetic cannabinoids increase the risk of harmful effects.
Related Compounds
CUMYL-4CN-BINACA is related to other synthetic cannabinoids such as AB-FUBINACA, ADB-PINACA, and 5F-ADB. These compounds share similar mechanisms of action and are often found in similar products.
See Also
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Contributors: Prab R. Tumpati, MD
