CACNA1I
CACNA1I is a gene that in humans encodes the calcium channel, voltage-dependent, T type, alpha 1I subunit. This gene is also known as Cav3.3 and is part of the calcium channel family.
Function[edit]
The protein encoded by the CACNA1I gene is a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
Clinical significance[edit]
Mutations in the CACNA1I gene have been associated with various psychiatric disorders, including schizophrenia, bipolar disorder, and major depressive disorder. Research has also suggested a potential link between CACNA1I and autism spectrum disorder.
See also[edit]
References[edit]
External links[edit]
| Genes on Human chromosome 22 | ||||||
|---|---|---|---|---|---|---|
This Human chromosome 22 related article is a stub.
|
| Voltage-gated ion channels | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
This voltage-gated ion channels related article is a stub.
|
Template:Calcium channel blockers
 | This medical article is a stub. You can help WikiMD by expanding the page. |
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
