Burkholderiales
Burkholderiales
Burkholderiales is an order of Proteobacteria, a major group of Gram-negative bacteria. This order is part of the class Betaproteobacteria, which includes a diverse range of bacteria that are found in various environments, including soil, water, and as pathogens of plants and animals.
Characteristics
Members of the order Burkholderiales are typically rod-shaped and motile, possessing flagella. They are known for their metabolic diversity, allowing them to thrive in a wide range of environments. Many species within this order are capable of degrading complex organic compounds, making them important in bioremediation.
Genera
The order Burkholderiales includes several genera, some of which are of significant medical and environmental importance:
- Burkholderia: This genus includes species such as Burkholderia pseudomallei, the causative agent of melioidosis, and Burkholderia cepacia, which is known for causing infections in patients with cystic fibrosis.
- Ralstonia: Known for Ralstonia solanacearum, a plant pathogen that causes wilt in a variety of crops.
- Cupriavidus: Includes Cupriavidus metallidurans, known for its ability to survive in heavy metal-contaminated environments.
Pathogenicity
Some members of Burkholderiales are notable pathogens. Burkholderia pseudomallei is a significant human pathogen causing melioidosis, a disease endemic in Southeast Asia and Northern Australia. The bacteria are found in soil and water and can infect humans and animals through cuts in the skin, inhalation, or ingestion.
Environmental Role
Apart from their pathogenic members, many Burkholderiales play crucial roles in the environment. They are involved in the nitrogen cycle and can degrade pollutants, contributing to the bioremediation of contaminated sites. Their ability to break down complex organic compounds makes them valuable in the treatment of industrial waste.
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Contributors: Prab R. Tumpati, MD