Aromatic alcohol
Aromatic alcohols are a type of organic compound that contain an aromatic ring and an alcohol group. They are a subclass of phenols and are important in a variety of fields, including chemistry, pharmacology, and perfumery.
Structure and Properties
Aromatic alcohols are characterized by the presence of an aromatic ring, a cyclic structure of atoms with alternating single and double bonds, and an alcohol group, which consists of a hydroxyl (-OH) group attached to a carbon atom. The most simple aromatic alcohol is phenol, which consists of a benzene ring attached to a hydroxyl group.
The properties of aromatic alcohols are largely determined by the nature of the aromatic ring and the position and number of the alcohol groups. They are generally more acidic than aliphatic alcohols due to the delocalization of the electron pair of the hydroxyl group into the aromatic ring.
Synthesis
Aromatic alcohols can be synthesized through a variety of methods. One common method is the reduction of aromatic nitro compounds, which involves the conversion of a nitro group (-NO2) to a hydroxyl group (-OH). Another method is the hydrolysis of aryl halides, which involves the replacement of a halide group (such as -Cl or -Br) with a hydroxyl group.
Uses
Aromatic alcohols have a wide range of uses. In chemistry, they are used as solvents and as starting materials for the synthesis of other compounds. In pharmacology, they are used in the production of a number of drugs, including antiseptics and analgesics. In perfumery, they are used for their pleasant, often floral, odors.
See Also
References
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Contributors: Prab R. Tumpati, MD