Antibe Therapeutics
Antibe Therapeutics Inc. is a Canadian biotechnology company focused on the development of novel, non-addictive therapies for pain and inflammation. The company is headquartered in Toronto, Ontario, and is publicly traded on the Toronto Stock Exchange under the ticker symbol ATE.
History
Antibe Therapeutics was founded in 2009 by Dr. John Wallace, a renowned scientist in the field of gastrointestinal health and inflammation. The company was established with the aim of addressing the significant unmet need for safer and more effective pain management solutions.
Technology
Antibe Therapeutics utilizes a proprietary hydrogen sulfide-releasing technology to develop its drug candidates. This technology is designed to enhance the safety and efficacy of existing drugs by releasing small amounts of hydrogen sulfide, a naturally occurring gas in the body that has anti-inflammatory and cytoprotective properties.
Pipeline
The company's lead drug candidate is ATB-346, a hydrogen sulfide-releasing derivative of naproxen, a widely used nonsteroidal anti-inflammatory drug (NSAID). ATB-346 is being developed for the treatment of osteoarthritis and other chronic pain conditions. Clinical trials have demonstrated that ATB-346 provides effective pain relief with significantly reduced gastrointestinal side effects compared to traditional NSAIDs.
Other drug candidates in Antibe's pipeline include ATB-352, a hydrogen sulfide-releasing derivative of ketoprofen, and ATB-340, a hydrogen sulfide-releasing derivative of aspirin.
Research and Development
Antibe Therapeutics is actively engaged in research and development to expand its pipeline of hydrogen sulfide-releasing drugs. The company collaborates with leading academic institutions and research organizations to advance its technology and explore new therapeutic applications.
Leadership
The company's leadership team includes experienced professionals from the biotechnology and pharmaceutical industries. Dr. John Wallace serves as the Chief Scientific Officer, and Dan Legault is the Chief Executive Officer.
See also
- Biotechnology
- Pharmaceutical industry
- Pain management
- Nonsteroidal anti-inflammatory drug
- Hydrogen sulfide
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Contributors: Prab R. Tumpati, MD
