Amyloid purpura
Amyloid Purpura
Amyloid purpura (pronunciation: /ˈæmɪˌlɔɪd ˈpɜːrpjʊrə/) is a medical condition characterized by the deposition of abnormal amyloid proteins in the blood vessels, leading to purpura or purple-colored spots and patches on the skin.
Etymology
The term 'Amyloid purpura' is derived from the Greek words 'amylon' meaning starch and 'purpura' meaning purple. 'Amyloid' refers to the starch-like nature of the protein deposits, while 'purpura' refers to the purple discoloration of the skin caused by small bleeding underneath the skin.
Symptoms
The primary symptom of Amyloid purpura is the appearance of purpura, or purple-colored spots and patches on the skin. These spots are caused by bleeding underneath the skin due to the weakening of blood vessels by amyloid deposits. Other symptoms may include fatigue, weight loss, and swelling in the legs and ankles.
Causes
Amyloid purpura is caused by the deposition of abnormal amyloid proteins in the blood vessels. This can occur as a result of various conditions, including chronic inflammatory diseases, genetic disorders, and certain types of cancer.
Diagnosis
Diagnosis of Amyloid purpura typically involves a physical examination, blood tests, and a biopsy of the affected skin or organ. Imaging tests such as ultrasound or MRI may also be used to assess the extent of amyloid deposits in the body.
Treatment
Treatment for Amyloid purpura primarily involves managing the underlying condition causing the amyloid deposits. This may include medication to reduce inflammation, chemotherapy for cancer, or genetic therapy for genetic disorders. In severe cases, organ transplantation may be necessary.
Related Terms
External links
- Medical encyclopedia article on Amyloid purpura
- Wikipedia's article - Amyloid purpura
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