Amifampridine
Amifampridine
Amifampridine (pronounced as am-ee-FAM-pri-deen) is a medication used to treat certain neuromuscular disorders. It is specifically used for Lambert-Eaton syndrome and Congenital Myasthenic Syndromes (CMS).
Etymology
The term "Amifampridine" is derived from its chemical name, 3,4-diaminopyridine. The prefix "ami-" is derived from "amino," referring to the presence of amino groups in the molecule. The "-fampridine" part is a modification of "pyridine," which is a basic heterocyclic organic compound.
Usage
Amifampridine works by blocking potassium channels on the nerve cells, which prolongs nerve signals and allows more calcium to enter the nerve endings. This, in turn, improves muscle strength.
Side Effects
Common side effects of Amifampridine include insomnia, nausea, diarrhea, back pain, and headache. Severe side effects may include seizures.
Related Terms
- Lambert-Eaton syndrome: A disorder of the neuromuscular junction leading to muscle weakness.
- Congenital Myasthenic Syndromes (CMS): A group of conditions characterized by muscle weakness and fatigue.
- Potassium channels: Channels located in the cell membrane, which allow potassium ions to pass.
- Calcium: A mineral essential for various body functions, including nerve function.
- Insomnia: Difficulty in falling asleep or staying asleep.
- Nausea: A feeling of sickness with an inclination to vomit.
- Diarrhea: A condition characterized by the frequent passage of loose or watery stools.
- Back pain: Pain felt in the back that usually originates from the muscles, nerves, bones, joints or other structures in the spine.
- Headache: A continuous pain in the head.
- Seizures: Changes in behavior or movement due to unusual electrical activity in the brain.
External links
- Medical encyclopedia article on Amifampridine
- Wikipedia's article - Amifampridine
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