4-Aminopyridine

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4-Aminopyridine (pronunciation: 4-uh-MEE-noh-PIE-ri-deen) is a drug primarily used for the management of certain neurological conditions. It is also known by its brand name, Ampyra.

Etymology

The term "4-Aminopyridine" is derived from its chemical structure, which consists of a pyridine ring with an amino group attached at the 4th position.

Pharmacology

4-Aminopyridine is a potassium channel blocker. It works by blocking potassium channels on the nerve cells, which enhances nerve conduction and improves the symptoms of certain neurological conditions.

Medical Uses

4-Aminopyridine is primarily used in the treatment of Multiple Sclerosis (MS). It helps to improve walking in adults with MS. It is also used off-label for other neurological conditions such as Lambert-Eaton Syndrome and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP).

Side Effects

Common side effects of 4-Aminopyridine include dizziness, headache, nausea, and insomnia. Serious side effects may include seizures, kidney problems, and allergic reactions.

Related Terms

See Also

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