Ameloblastic fibroma

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Ameloblastic Fibroma

Ameloblastic fibroma (pronunciation: a-me-lo-blas-tic fi-bro-ma) is a rare, benign odontogenic tumor that originates from the odontogenic epithelium and mesenchyme. The term "ameloblastic fibroma" is derived from the Greek words "amelos" meaning enamel and "blastos" meaning germ, combined with "fibroma" which is a tumor composed of fibrous or connective tissue.

Definition

Ameloblastic fibroma is a slow-growing, painless neoplasm that typically occurs in the posterior region of the lower jaw, or mandible. It is most commonly diagnosed in the first two decades of life, with a slight male predilection.

Clinical Features

Clinically, ameloblastic fibroma presents as a swelling or expansion of the jaw. Radiographically, it appears as a well-defined, unilocular or multilocular radiolucent lesion. The tumor is often associated with an unerupted tooth, particularly the molars or premolars.

Histopathology

Histologically, ameloblastic fibroma is characterized by the presence of proliferating odontogenic epithelium embedded in a cellular mesenchymal stroma, resembling dental papilla. The epithelial component consists of strands, cords, and islands of ameloblastic epithelium.

Treatment and Prognosis

The treatment of choice for ameloblastic fibroma is conservative surgical excision, with a good prognosis following complete removal. Recurrence is rare but can occur, particularly if the lesion is not completely excised.

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