Aeruginascin
A tryptamine derivative found in certain mushrooms
Aeruginascin is a tryptamine derivative that is found in certain species of mushrooms, notably Inocybe aeruginascens. It is chemically related to psilocybin and psilocin, which are well-known psychedelic compounds. Aeruginascin is believed to contribute to the psychoactive effects of these mushrooms.
Chemical structure and properties
Aeruginascin is a trimethylammonium salt of psilocybin, making it a quaternary ammonium compound. Its chemical structure is similar to that of psilocybin, with the addition of a trimethylammonium group. This structural modification affects its pharmacological properties and its interaction with the human body.
Occurrence
Aeruginascin is primarily found in the mushroom species Inocybe aeruginascens. This species is known for its psychoactive properties and is native to certain regions in Europe. The presence of aeruginascin, along with psilocybin and psilocin, contributes to the overall psychoactive profile of these mushrooms.
Pharmacology
The pharmacological effects of aeruginascin are not as well-studied as those of psilocybin and psilocin. However, it is believed to interact with the serotonin receptors in the brain, similar to other tryptamine derivatives. This interaction is thought to be responsible for its psychoactive effects.
Effects
The effects of aeruginascin are not well-documented, but it is assumed to produce effects similar to those of psilocybin and psilocin, including altered perception, mood changes, and cognitive effects. The presence of the trimethylammonium group may alter the intensity or duration of these effects.
Safety and legal status
As with other psychoactive compounds found in mushrooms, the legal status of aeruginascin varies by country. In many places, mushrooms containing aeruginascin are classified as controlled substances, making their possession, sale, or use illegal. The safety profile of aeruginascin is not well-established, and caution is advised when dealing with mushrooms containing this compound.
Related pages
Gallery
Chemical structure of aeruginascin
Inocybe aeruginascens mushroom
Aeruginascin.svg
Inocybe_aeruginascens.jpg
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Contributors: Prab R. Tumpati, MD
