Adanon

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Adanon', better known as Methadone, is a synthetic opioid agonist, marketed under brand names such as Dolophine and Methadose among others. It is primarily used in the management of chronic pain and for the treatment of opioid use disorder, including addiction to heroin and other opioids.

Pronunciation

Ah-dah-non for Adanon; Meth-uh-done for Methadone.

Etymology

The name "Methadone" is derived from its chemical name: 6-(dimethylamino)-4,4-diphenyl-3-heptanone. The brand name "Adanon" does not have a publicly disclosed etymology but is one of the many commercial names for Methadone.

Pharmacodynamics

Methadone works by acting on the mu-opioid receptor (MOR) in the brain and nervous system, similar to other opioids but with a longer duration of action. Its effectiveness in treating opioid addiction is attributed to its ability to reduce craving and withdrawal symptoms without producing the euphoria associated with the abused drug. Methadone's utility in chronic pain management is due to its analgesic properties.

Clinical Uses

  • Chronic Pain Management: Methadone is prescribed for the long-term treatment of chronic pain, offering benefits for patients requiring continuous pain management.
  • Opioid Use Disorder: It is a cornerstone in the medication-assisted treatment (MAT) of opioid addiction, helping individuals reduce or quit their use of heroin or other opioids.

Related Terms

See Also

External links

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