Accelerated phase chronic myelogenous leukemia

From Food & Medicine Encyclopedia


Accelerated phase chronic myelogenous leukemia
Synonyms Accelerated phase CML
Pronounce N/A
Specialty N/A
Symptoms Fatigue (medical), fever, weight loss, splenomegaly, bone pain
Complications Blast crisis, anemia, thrombocytopenia
Onset Typically in middle age
Duration Chronic, with progression
Types N/A
Causes Philadelphia chromosome (BCR-ABL1 fusion gene)
Risks Radiation exposure, genetic predisposition
Diagnosis Complete blood count, bone marrow biopsy, cytogenetic analysis
Differential diagnosis Chronic myelogenous leukemia, acute myeloid leukemia, myelodysplastic syndrome
Prevention N/A
Treatment Tyrosine kinase inhibitors, chemotherapy, hematopoietic stem cell transplantation
Medication N/A
Prognosis Variable, depends on response to treatment
Frequency Rare, as a phase of chronic myelogenous leukemia
Deaths N/A


a phase of chronic myelogenous leukemia characterized by one or more of the following

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