ADB-4en-PINACA

ADB-4en-PINACA_structure.png

ADB-4en-PINACA
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number
PubChem
DrugBank
ChemSpider
KEGG

ADB-4en-PINACA is a synthetic cannabinoid that has been identified in synthetic cannabis products. It is a potent agonist of the CB1 receptor and CB2 receptor, which are part of the endocannabinoid system.

Chemical Structure

ADB-4en-PINACA belongs to the indazole family of synthetic cannabinoids. Its chemical structure includes a fluorobutyl side chain, which is a distinguishing feature among synthetic cannabinoids. The IUPAC name for ADB-4en-PINACA is N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobutyl)-1H-indazole-3-carboxamide.

Pharmacology

As a synthetic cannabinoid, ADB-4en-PINACA acts on the CB1 receptor and CB2 receptor in the endocannabinoid system. These receptors are primarily found in the central nervous system and immune system, respectively. The activation of these receptors by synthetic cannabinoids can lead to a range of effects, including euphoria, anxiety, and hallucinations.

Legal Status

The legal status of ADB-4en-PINACA varies by country. In some jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. For example, in the United States, synthetic cannabinoids are often regulated under the Controlled Substances Act.

Health Risks

The use of ADB-4en-PINACA has been associated with a number of adverse health effects. These can include tachycardia, hypertension, nausea, and vomiting. In severe cases, it can lead to psychosis and seizures. Due to these risks, the use of synthetic cannabinoids like ADB-4en-PINACA is generally discouraged.

See Also

• Synthetic cannabinoids
• Endocannabinoid system
• CB1 receptor
• CB2 receptor