5-MeO-isoDMT

Chemical compound

5-MeO-isoDMT
INN
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CAS Number	104404-18-4
PubChem	443850
DrugBank
ChemSpider	392063
KEGG

5-Methoxy-N,N-dimethyltryptamine (5-MeO-isoDMT) is a psychedelic compound belonging to the tryptamine class. It is structurally related to other tryptamines such as 5-MeO-DMT and N,N-DMT, but it is distinguished by the presence of a methoxy group at the 5-position of the indole ring.

Chemical Structure and Properties

5-MeO-isoDMT is a synthetic compound with the chemical formula C₁₃H₁₈N₂O. The structure consists of an indole ring, which is a common feature in many biologically active compounds, including the neurotransmitter serotonin. The methoxy group at the 5-position and the dimethylamino group attached to the ethyl side chain are characteristic of this compound.

Chemical structure of 5-MeO-isoDMT

Pharmacology

The pharmacological effects of 5-MeO-isoDMT are not well-documented, but it is believed to act as a partial agonist at the 5-HT_2A receptor, similar to other psychedelic tryptamines. This receptor is known to play a significant role in the modulation of mood, perception, and cognition.

Effects

The effects of 5-MeO-isoDMT are largely anecdotal and have not been extensively studied in clinical settings. Users report experiences similar to those of other tryptamines, including altered states of consciousness, visual and auditory hallucinations, and changes in perception of time and space. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.

Legal Status

The legal status of 5-MeO-isoDMT varies by country. In some jurisdictions, it may be classified as a controlled substance, while in others it may not be specifically regulated. It is important for individuals to be aware of the legal implications of possessing or using this compound in their respective regions.

Synthesis

The synthesis of 5-MeO-isoDMT typically involves the methylation of the indole nitrogen of 5-methoxytryptamine. This process can be achieved through various chemical reactions, including the use of methylating agents such as methyl iodide or dimethyl sulfate.

Related Compounds

5-MeO-isoDMT is part of a broader class of compounds known as tryptamines, which includes a variety of naturally occurring and synthetic substances. Related compounds include:

• 5-MeO-DMT
• N,N-DMT
• Bufotenin

Related Pages

• Psychedelic drug
• Serotonin receptor
• Tryptamine