4-Nonylphenylboronic acid

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Chemical compound



4-Nonylphenylboronic acid

Structure of 4-Nonylphenylboronic acid

4-Nonylphenylboronic acid is an organic compound that belongs to the class of boronic acids. It is characterized by the presence of a phenyl group substituted with a nonyl group and a boronic acid functional group.

Chemical structure

The chemical structure of 4-Nonylphenylboronic acid consists of a benzene ring with a nonyl group attached to the para position, and a boronic acid group (B(OH)_) attached to the benzene ring. The presence of the boronic acid group makes it a useful reagent in organic synthesis, particularly in Suzuki coupling reactions.

Properties

4-Nonylphenylboronic acid is typically a solid at room temperature. It is soluble in organic solvents and can form complexes with diols and other Lewis bases. The boronic acid group allows it to participate in reversible covalent bonding, which is useful in various chemical applications.

Applications

4-Nonylphenylboronic acid is used in the synthesis of biaryl compounds through Suzuki-Miyaura coupling, a type of cross-coupling reaction that forms carbon-carbon bonds. This reaction is widely used in the pharmaceutical industry for the synthesis of complex organic molecules.

Safety and handling

As with many chemical compounds, proper safety precautions should be taken when handling 4-Nonylphenylboronic acid. It should be stored in a cool, dry place and handled with appropriate personal protective equipment to avoid exposure.

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Contributors: Prab R. Tumpati, MD