4'-Methoxy-α-pyrrolidinopropiophenone

Chemical compound

4'-Methoxy-α-pyrrolidinopropiophenone (also known as MOPPP) is a synthetic stimulant of the cathinone class. It is chemically related to α-pyrrolidinopropiophenone (α-PPP) and is known for its psychoactive effects. MOPPP has been encountered as a designer drug and is subject to various legal controls in different jurisdictions.

Chemical Structure and Properties

Chemical structure of MOPPP

MOPPP is a derivative of α-PPP, with a methoxy group attached to the para position of the phenyl ring. Its chemical formula is C14H19NO2, and it has a molecular weight of 233.31 g/mol. The presence of the methoxy group is believed to influence its pharmacological activity.

Pharmacology

MOPPP acts as a central nervous system stimulant. It is thought to exert its effects by increasing the levels of neurotransmitters such as dopamine and norepinephrine in the brain, similar to other stimulants like amphetamine. This action is primarily due to its ability to inhibit the reuptake of these neurotransmitters, leading to increased synaptic concentrations.

Effects

The effects of MOPPP are similar to those of other stimulants and may include increased alertness, euphoria, and enhanced physical performance. However, it can also cause adverse effects such as anxiety, paranoia, and cardiovascular issues. The intensity and duration of these effects can vary depending on the dose and route of administration.

Legal Status

MOPPP is classified as a controlled substance in several countries due to its potential for abuse and lack of medical use. It is often included in legislation targeting designer drugs and novel psychoactive substances.

Related Compounds

Chemical structure of α-PPP

MOPPP is closely related to other compounds in the pyrrolidinophenone family, such as α-PPP and MDPPP. These compounds share a similar core structure but differ in their substituents, which can significantly alter their pharmacological profiles.

Synthesis

The synthesis of MOPPP involves the reaction of 4'-methoxypropiophenone with pyrrolidine. This process is similar to the synthesis of other pyrrolidinophenone derivatives and requires careful control of reaction conditions to ensure the desired product is obtained.

Health Risks

The use of MOPPP carries significant health risks, particularly due to its stimulant properties. Users may experience increased heart rate, hypertension, and risk of cardiac arrest. Long-term use can lead to psychological dependence and other mental health issues.

Related Pages

• Cathinone
• Designer drug
• Stimulant
• Amphetamine

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Chemical structure of Amphetamine

See Also

• 4-Methylmethcathinone (Mephedrone)
• Methamphetamine
• Phenethylamine