4'-Methoxy-α-pyrrolidinopentiophenone
| 4'-Methoxy-α-pyrrolidinopentiophenone | |
|---|---|
| MOPVP.svg | |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | 13415-87-5 |
| PubChem | 119025 |
| DrugBank | |
| ChemSpider | 106282 |
| KEGG | |
4'-Methoxy-α-pyrrolidinopentiophenone (also known as MOPVP) is a synthetic stimulant of the cathinone class. It is chemically related to α-PVP and is known for its psychoactive effects. MOPVP is a designer drug that has been sold online as a recreational drug.
Chemical structure and properties[edit]
MOPVP is a derivative of α-pyrrolidinopentiophenone (α-PVP), where a methoxy group is attached to the para position of the phenyl ring. The chemical formula of MOPVP is C16H23NO2, and it has a molar mass of 261.36 g/mol. The presence of the methoxy group is thought to influence the compound's pharmacological properties, potentially altering its potency and duration of action compared to its analogs.
Pharmacology[edit]
MOPVP acts as a norepinephrine-dopamine reuptake inhibitor (NDRI), similar to other synthetic cathinones. This mechanism of action leads to increased concentrations of norepinephrine and dopamine in the synaptic cleft, resulting in stimulant effects. Users report effects such as increased energy, euphoria, and enhanced focus. However, the drug can also cause adverse effects such as anxiety, paranoia, and cardiovascular issues.
Legal status[edit]
The legal status of MOPVP varies by country. In many jurisdictions, it is classified as a controlled substance due to its structural similarity to other banned synthetic cathinones. In the United States, for example, it may be considered an analogue of α-PVP, which is a Schedule I controlled substance under the Controlled Substances Act.
Health risks[edit]
The use of MOPVP carries significant health risks. As with other synthetic stimulants, there is a potential for abuse and addiction. Acute adverse effects can include tachycardia, hypertension, hyperthermia, and seizures. Chronic use may lead to psychological dependence and cognitive impairments. Due to the lack of clinical studies, the long-term effects of MOPVP are not well understood.