2-Fluoromethcathinone

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2-Fluoromethcathinone

Chemical structure of 2-Fluoromethcathinone

2-Fluoromethcathinone, also known as 2-FMC, is a synthetic stimulant of the cathinone class. It is a fluorinated derivative of methcathinone, a compound that is structurally related to cathinone, the active constituent of the khat plant. 2-FMC is part of a group of substances commonly referred to as "designer drugs" or "research chemicals".

Chemical Structure and Properties

2-Fluoromethcathinone is chemically similar to methcathinone, with the primary difference being the substitution of a fluorine atom at the 2-position of the phenyl ring. This modification is thought to influence the compound's pharmacological properties, potentially altering its potency, duration of action, and metabolic pathway.

The chemical formula of 2-FMC is C10H12FNO, and it has a molecular weight of 181.21 g/mol. The presence of the fluorine atom is a common modification in the development of new psychoactive substances, as it can significantly affect the compound's interaction with biological targets.

Pharmacology

2-Fluoromethcathinone acts as a central nervous system stimulant. It is believed to exert its effects primarily by increasing the levels of neurotransmitters such as dopamine, norepinephrine, and serotonin in the brain. This is achieved through the inhibition of their reuptake into presynaptic neurons, similar to the mechanism of action of other cathinones and amphetamine-like stimulants.

The exact pharmacokinetics of 2-FMC, including its absorption, distribution, metabolism, and excretion, have not been extensively studied. However, it is likely that the compound is metabolized in the liver and excreted via the kidneys, similar to other substances in its class.

Effects and Risks

The effects of 2-Fluoromethcathinone are reported to be similar to those of other stimulant drugs, including increased alertness, euphoria, and enhanced physical and cognitive performance. However, the use of 2-FMC also carries significant risks, including the potential for addiction, cardiovascular complications, and neurotoxicity.

Adverse effects may include anxiety, paranoia, insomnia, and tachycardia. The long-term health effects of 2-FMC use are not well understood, and its safety profile remains largely unknown due to the lack of comprehensive clinical studies.

Legal Status

The legal status of 2-Fluoromethcathinone varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. In the United States, for example, it may be considered an analogue of methcathinone, making it subject to the Federal Analogue Act.

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