2β-Propanoyl-3β-(4-tolyl)-tropane

2β-Propanoyl-3β-(4-tolyl)-tropane (WF-23) is a cocaine analogue. It is a potent stimulant and a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).

Chemistry

2β-Propanoyl-3β-(4-tolyl)-tropane, also known as WF-23, is a synthetic analogue of cocaine. It has a similar structure to cocaine, but with a toluene ring replacing the benzoyl group. This modification results in a compound with increased potency and duration of action compared to cocaine.

Pharmacology

WF-23 acts as a potent SNDRI, inhibiting the reuptake of serotonin, norepinephrine, and dopamine. This results in increased concentrations of these neurotransmitters in the brain, leading to increased stimulation and euphoria. The exact mechanism of action of WF-23 is not fully understood, but it is believed to bind to the transporter proteins responsible for the reuptake of these neurotransmitters, preventing their removal from the synaptic cleft.

Effects

The effects of WF-23 are similar to those of cocaine, but are more potent and longer-lasting. These effects include increased alertness, euphoria, increased heart rate and blood pressure, and potential for addiction. Due to its potency and long duration of action, WF-23 has a high potential for abuse and addiction.

Legal Status

WF-23 is a controlled substance in many countries due to its similarity to cocaine and its potential for abuse and addiction. In the United States, it is classified as a Schedule II controlled substance under the Controlled Substances Act.

See Also

• Cocaine
• Stimulant
• Serotonin-norepinephrine-dopamine reuptake inhibitor

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  WF-11 structure