Α-Pyrrolidinohexiophenone

Synthetic stimulant of the cathinone class

Α-Pyrrolidinohexiophenone
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α-Pyrrolidinohexiophenone (α-PHP) is a synthetic stimulant of the cathinone class that has been sold online as a designer drug. It is structurally related to α-PVP and is known for its stimulant effects.

Chemical structure and properties

α-PHP is a cathinone derivative, which is a class of compounds that are chemically similar to amphetamines. The chemical structure of α-PHP includes a pyrrolidine ring, which is a common feature in many synthetic cathinones. This structural feature is believed to contribute to its stimulant properties.

Chemical structure of α-PHP

The molecular formula of α-PHP is C16H23NO, and it has a molar mass of 245.36 g/mol. The presence of the pyrrolidine ring distinguishes it from other cathinones, such as mephedrone and methcathinone.

Pharmacology

α-PHP acts as a norepinephrine-dopamine reuptake inhibitor (NDRI), which means it increases the levels of the neurotransmitters norepinephrine and dopamine in the brain. This action is similar to that of other stimulants, leading to increased alertness, energy, and euphoria.

The effects of α-PHP are dose-dependent and can vary significantly between individuals. Common effects include increased heart rate, elevated blood pressure, and enhanced mood. However, higher doses can lead to adverse effects such as anxiety, paranoia, and hallucinations.

Usage and effects

α-PHP is typically consumed for its stimulant effects, which are sought after for recreational purposes. Users report effects similar to those of other stimulants, such as increased sociability, energy, and focus. However, the use of α-PHP is associated with significant risks, including the potential for addiction and adverse psychological effects.

α-PHP in powder form

Legal status

The legal status of α-PHP varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. In the United States, for example, α-PHP is listed as a Schedule I substance under the Controlled Substances Act.

Health risks

The use of α-PHP carries several health risks, particularly when used in high doses or over extended periods. Acute effects can include cardiovascular issues such as tachycardia and hypertension, as well as psychological effects like anxiety and paranoia. Chronic use may lead to dependence and withdrawal symptoms upon cessation.

Related pages

• Cathinone
• Synthetic cathinones
• Designer drug
• Norepinephrine-dopamine reuptake inhibitor