Α-Pyrrolidinobutiophenone

Synthetic stimulant of the cathinone class

Α-Pyrrolidinobutiophenone
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α-Pyrrolidinobutiophenone (also known as α-PBP) is a synthetic stimulant of the cathinone class that has been sold online as a designer drug. It is chemically related to α-Pyrrolidinopentiophenone (α-PVP) and is known for its stimulant effects.

Chemical structure and properties

Chemical structure of α-PBP

α-PBP is a derivative of cathinone, which is a naturally occurring stimulant found in the khat plant. The chemical structure of α-PBP includes a pyrrolidine ring, which is a common feature in many synthetic cathinones. This structural feature is believed to contribute to its stimulant properties by affecting the reuptake of neurotransmitters such as dopamine and norepinephrine.

Pharmacology

α-PBP acts as a norepinephrine-dopamine reuptake inhibitor (NDRI), which means it increases the levels of these neurotransmitters in the brain by preventing their reabsorption into neurons. This action is similar to that of other stimulants, such as amphetamines and cocaine, and is responsible for the drug's stimulating effects.

Effects and use

The effects of α-PBP are similar to those of other stimulants and may include increased alertness, euphoria, and enhanced physical and mental performance. However, these effects are often accompanied by undesirable side effects such as anxiety, paranoia, and increased heart rate. Due to its potency and potential for abuse, α-PBP is considered a substance of concern in many countries.

Legal status

The legal status of α-PBP varies by country. In some jurisdictions, it is classified as a controlled substance, making its production, distribution, and possession illegal. In others, it may be regulated under analog laws that control substances similar to those already banned.

Health risks

Molecular structure of α-PBP

The use of α-PBP carries significant health risks, particularly when used in high doses or in combination with other substances. Potential adverse effects include cardiovascular problems, neurological issues, and psychological disturbances. Long-term use can lead to addiction and other serious health complications.

Related pages

• Cathinone
• Synthetic cathinones
• Designer drug
• Norepinephrine-dopamine reuptake inhibitor